Lisa Marie Simpson, voiced by Yeardley Smith, is Homer and Marge's oldest duaghter and the middle child on The Simpsons.  Lisa is very intelligent, plays the saxophone, is a vegetarian, Buddhist, and definitely a bit of a young political activist.  She's basically the complete opposite of her brother, Bart.

Lisa Simpson Quotes

Bart: I'll go, disguised as you.
Lisa: What if he wants to hold hands?
Bart: I'm prepared to make that sacrifice.
Lisa: What if he wants a kiss?
Bart: I'm prepared to make that sacrifice.
Lisa: What if he
Bart: You don't want to know how far I'll go.

Bart and Lisa: (Singing dull) Hot dogs, Armour Hot Dogs.
Grampa: Sing it like you mean it!
(Grampa plays harmonica and the kids sing it with style.)
Bart and Lisa: What kind of kids eat Armour Hot Dogs?
Bart: Fat kids.
Lisa: Skinny kids.
Bart: Kids who climb on rocks.
Lisa: Tough kids.
Bart: Sissy kids.
Milhouse: (Sticks head from the window.) Even kids with chicken pox love--
Family: Hot dogs, Armour Hot Dogs.
(Grampa stops playing harmonica.) The dogs kids love to bite!
Lisa: Doesn't this family know any songs that aren't commercials?
(Everyone except Lisa starts singing the "Chicken Tonight" jingle.)

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The Simpsons Quotes

Mr. Burns: Oh, and one more thing: you must find the jade monkey before the next full moon.
Smithers Actually sir, we found the jade monkey. It was in your glove compartment.
Mr. Burns: And the road maps, and ice scraper?
Smithers: They were in there too, sir.
Mr. Burns: Excellent! It's all falling into place...

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!