Meredith, Cristina and George in a photo from "Elevator Love Letter."

Remember Gizzie? As in George and Izzie? You can be forgiven if you don't, but here they are in a cute, recent photo.

George sighting! George sighting! Will O'Malley actually have a central role in this episode? Here's hoping.

A picture of Lexie and George, talking things out. Do we think she still wants him after she blew up at him the last time? We'll see...

Well, not that kind of action. But there's a lot of activity in this photo from "There's No 'I' in Team," from Season Five of Grey's Anatomy, as the residents discuss their respective days.

George O'Malley is now a resident at long last! How will he respond now that he has interns? Here's our guy in this photo from "There's No 'I' in Team," from Season Five of Grey's Anatomy.

George and Izzie look a little tipsy in a photo from "Brave New World" from Season Five of Grey's Anatomy. Good to see them hanging out again!

George and Izzie smile at each other in a photo from "Brave New World" from Season Five of Grey's Anatomy. These two used to be best friends, then hooked up, then broke up. What next?

George talks to Meredith and Izzie in a photo from "Brave New World" from Season Five of Grey's Anatomy. He has slept with both of them! Amazing.

Dr. George O'Malley is back and better than ever in a photo from "Brave New World" from Season Five of Grey's Anatomy. Eh, he's just George, but that's why we love him.

Cristina and George look on in a photo from "Brave New World" from Season Five of Grey's Anatomy.

In a photo from "Brave New World," from Season 5, Richard gives George one of his usual talkings to. Wonder what about?