I'm done. I don't want to be your friend anymore. Find another way home.

Mika [to Lucas]

Winston: We were supposed to talk about what's next for us, just like we were supposed to do last week, and the week before. But there's always a class or paper. At what point do I stop trying?
Owen: I don't think that's the question. The better question is, why? Why are you trying?

Owen: You don't stop until you've got the final answer. You don't stop until you save them or you find out that they're.. that they're dead.
Megan: Owen, this guy isn't me.

Owen: What is he doing?
Meredith: He likes to teach. When he's pissed, he really likes to teach.

Richard: What do we need to know in order to do our jobs and not simply be mechanics?
Owen: How are we... we're not being mechanics!
Richards: You're treating this patient like a sack of organs on a table.

Amelia: Owen, there's nothing to talk about.
Owen: But you love to talk, and you're not talking about this at all.

Amelia: We're okay, right?
Owen: We're okay.
Amelia: And our kids will be okay?
Owen: Our kids will be amazing.

Owen: She's asks me a question, and I answer it, and my answer just causes more questions, and suddenly I've forgotten what we were talking about, and I'm late for work, and I love her, and it's exhausting.
Meredith: You feel better?
Owen: Yeah, a little bit.

Amelia: I don't have any more to give. I'm not trying to hurt you.
Owen: I'm not hurt. I get it. And I'm done.

Amelia: I know I'm a risk.
Owen: We're all a risk. We all have something.

Stop asking me out on dates.

Go easy on these guys. They can’t all be you.

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey