Stand up is so 20 years ago. Twitter's only three years ago.

Brian: You've been hanging out with Tom Cruise?
Stewie: Sure have. We spent the whole day together, and he showed me there are a lot of advantages to being short.
Brian: Yeah? Like what? You're the last one to get wet when it rains?

Stewie: Doesn't it boether you being an adult man who's that short, 'cause the doctor said that's where I'm headed.
Tom Cruise: No way, man. In the middle of the word short is "or". Or gives you a choice, and I choose not to be short.
Stewie: Wow. You need a road map for that one.

Tom Cruise: Nobody walks away from tiny Tom Cruise.
Stewie: Yeah, except for all three of your wives.

Hey? You up? Guess where I have a crayon?

Stewie: Yes looks like someone's gone at him with a whip.
Brian: That is a perfectly valid way of saying that. Bravo master.
Stewie: Master? Aaand a surprisingly quick erection for Stewie.

Oh yeah 'cause you know him so well, shut your faaaaaace.

The new maid is peeing on me, and she didn't even say anything clever!

I feel like once I get them on a schedule, every thing will be fine!

Brian: This one's bones feel all loose.
Stewie: I think this one's blind.

I caught two of them trying to eat each other, so that's something we need to watch out for.

Brian save the placenta! Save it, I want to eat it.

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire