I'm dead. How do you want to spend your last five months?

House [to Wilson]

Is this hell? An eternity of people trying to convince me to live?

Don't be logical. Be desperate.

Stacy

House: He's happy.
Amber: He's dead.

I know you'll do the honest thing. You'll lie.

Foreman: You're stealing this guy's oxygen!
House: There's oxygen everywhere.

Death;s not interesting. You exist for what's interesting.

Kutner

I can't even get stoned without some annoying jerk thinking I need to be analyzed.

From what I hear, nothing black is tiny. Except your penis.

House [to Foreman]

I think it's time to accept you're smarter than me.

House (to Wilson)

Taub: You know he just doesn't want to live in pain.
House: Life is pain! I wake up every morning in pain! Work is pain! You know how many times I just wanted to give up? How many times I've thought about ending it?

Our entire relationship is about you. My dying is about me!

Wilson

House Quotes

House: You asked me how I'd hurt my leg. I had a blood clot, and the muscle was dying. And I had all these doctors telling me I should amputate, and I said no, and they did this... very risky operation. I almost died.
Hanna: But you saved your leg.
House: I wish I hadn't. They cut out a chunk of muscle about the size of my fist, and they left me with this mutilated, useless thing. I'm in pain... every day. It changed me. Made me a harder person. A worse person. And now... now I'm alone.You don't want to be like me.

My head's on your vagina.

House