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Sheldon invites a famous female physicist, Dr. Plimpton (Judy Greer) to stay at their place for the weekend while she's in town applying for a job.  She ends up sneaking behind a sexually uninterested Sheldon's back and sleeping with Leonard.  Penny finds out the next morning that Leonard slept with her and is clearly bothered by her ex moving on so fast.  Soon Plimpton begins hitting on anything that moves and tries to have an orgy with Leonard, Wolowitz and Raj, but ends up with just a Raj.

The Big Bang Theory
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The Big Bang Theory Season 3 Episode 21 Quotes

I have a lady friend who will be staying with me for a few days. I want her to feel at home; I also bought scented soaps, pantyhose, Midol, calcium chews, and what is apparently a yogurt specifically designed to regulate the female bowel.


Leonard: Are you planning on kidnapping a woman?
Sheldon: Sarcasm?
Leonard: Yes, but mixed with a little bit of concern.