Through its amounting seasons, Grey's Anatomy is certainly among the few major shows that aren't afraid to kill off characters.
Perhaps a bit too unrealistic with the actual number of tallied deaths, but it keeps viewers on edge wondering whose fateful ending is coming next.
Although emotionally charged, each death brought along many life lessons to the doctors of Grey Sloan Memorial. It allowed for the growth of many, and for the show to progress in a beautiful way.
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Undoubtedly one of the hardest on Grey's Anatomy, George O'Malley's passing in the last episode of Season 5 allowed for the interns and the doctors to experience their first impactful death of the show. The moment the audience realized nobody on the show was safe from getting killed off.
Meredith's complicated relationship with her mother was never resolved, but the easy and quick solution was Ellis' death in Season 3 Episode 17. Her death led to Meredith's freedom from any residual and lingering feelings of guilt or anger.
Samuel Norbort Avery
April and Jackson's son's death was short-lived for viewers, but, stayed forever with Jackson and April. His death on Season 11 Episode 9 seemed to bring up a lot of questions within April's faith, while also weakening the overall relationship of Japril. However, it taught them both many lessons as parents and as humans.
Richard Webber's relationship with his wife was surface-level sweet, but his complicated relationship with Ellis Grey created a murky under-depth. Richard's bereavement process was perhaps not the healthiest, but it brought him peace once he found happiness between the sadness.
Lexie Grey added another death to the total of Meredith's family members who died tragically. Lexie's death on Season 8 Episode 24 was definitely one of the most tragic, and among the most hard-hitting on the show. It sadly added another layer to Meredith's thick emotional skin, but it allowed for the growth of the hospital.
Mark's death in Season 9 Episode 2 perfectly aligned with Lexie's, and only added to the grief of the hospital at the time. A hard one for Callie, but perhaps subtracted a confounding factor to the complications of Callie and Arizona's relationship.