Sheldon and Stuart Put Penny to Sleep
When Sheldon crashes in on Stuart (Kevin Sussman) and Penny's date, he ends up arguing with Stuart on comic books until they put Penny and Stuart's chances of getting lucky to sleep.

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The Big Bang Theory
The Big Bang Theory Season 2 Episode 20: "The Hofstadter Isotope"
Sheldon Cooper, Penny
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The Big Bang Theory Season 2 Episode 20 Quotes

Raj: The Wolowitz coefficient?
Wolowitz: Neediness times dress size squared

Leonard: But we all agreed the third Thursday of every month will be "Anything Can Happen Thursday"
Sheldon: Apparently the news didn't reach my digestive system, which when startled has it's own version of "Anything Can Happen Thursday"