Watch The Big Bang Theory Season 5 Episode 16 online via TV Fanatic with over 6 options to watch the The Big Bang Theory S5E16 full episode. Affiliates with free and paid streaming include Amazon, iTunes, Vudu, YouTube Purchase, Google Play, and Verizon On Demand.

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Episode Details

Sheldon tries to take a vacation this week, by working with Amy at her neurobiology lab. Howard, meanwhile, gets all worked up.

Rating: 4.5 / 5.0 (106 Votes)
The Big Bang Theory
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The Big Bang Theory Season 5 Episode 16 Quotes

Good Lord! Would you stop that caterwauling?


I hear Afghanistan is nice this time of year.

University President