Dean and Sam are wheeling in the patient, although this photo is a little misplaced. We'll soon find out just where it belongs in the scope of things and what kind of entity they're dealing with as the premiere airs on Wednesday, Oct. 7 at 9/8!

Sam is in the hospital seemingly minding his own business while things appear to fall to hell behind him. Whatever is going down is leaving bodies bloodied and battered in its wake. Some hospital, right?

Dean takes a cautionary peek down the hall before proceeding any further. Hey, he's protecting a baby. So while he didn't smile once in any of these photos, at least he continues to take his job seriously!

Dean is providing protection for the sheriff and the baby inside the halls of the hospital. Against what, is the question. Has the Darkness already arrived or is there something else at play for the premiere?

Dean is taking care of his girl. He probably has a closer relationship with his Impala than any other lady he'll meet in his lifetime. However, if he should have one similar, it's good to know how well cared for she will be.

That is one sexy sneer coming off the face of Dean Winchester! If handing big weapons outside a hospital does that to the man, then they should park the Impala nearby the infirmed more often! Oh shush. Admit it, he's hot.

Dean and Sam are helping out a friend. And they're still arguing while doing it. Something just doesn't feel right about this episode at all, right? Darkness, indeed!

From the photos, it appears this is the baby daddy, but it's unclear how the sherriff fits into the narrative. She's later in a wheelchair. If she's the mother, she was working very late into her pregnancy!

Again, this isn't the tone you'd expect Dean to take upon a happy occassion such as the birth of a baby, right? So what is up with the baby? We don't have too long to wait to find out!

There's a baby, but neither Sam nor Dean looks very pleased at its appearance. Word is Darkness will take on the form of a specific entity, and a she to boot. Could it start out as a baby, and this one in particular? That wouldn't be a reason to smile.

It's Sam! How we've missed you, Sam. The brothers will be up against the Darkness, a pre-biblical foe who was defeated by God years ago. Sam is shown reaching out to God in the trailer. Can he be of help again? You'd think he might be angry the Winchesters released Darkness after it's already been banished.

Crowley likes to talk to young men in pairs, apparently. When the Winchester brothers aren't around, he'll find another pair of young men to take their place! What do you think he knows about the Darkness? Was she ever mentioned in his social circles?